» HHT FOUNDATION INTERNATIONAL: REQUEST FOR PROPOSALS
Research Program: Mechanisms of Disease in HHT
Description
The HHT Foundation’s goal is to stimulate and sponsor research into the diagnosis, mechanisms, treatment and cure of Hereditary Hemorrhagic Telangiectasia (HHT). There is currently little effective therapy available for many aspects of HHT. The HHT Foundation International would like to sponsor research leading to a better understanding of the underlying mechanisms of disease in HHT, with the ultimate goal of developing novel therapies for HHT.
Relevant Research Areas
The HHT Foundation International supports research including, but not limited to, priority areas identified during the NIH HHT Workshop (June 2006). These are detailed at http://www.genome.gov/19519386 and include various aspects of TGF-beta pathway, vascular biology, cell biology and organ pathophysiology research in HHT.
Funds Available
Grants may be awarded for one or two years, up to a maximum of $50,000 US.
Eligibility
Grant applications may be submitted by international principal investigators. Post-doctoral students or fellows are not eligible to apply as principal investigators for this RFP. Basic science researchers are encouraged to apply, including, but not limited to, vascular biologists, molecular biologists, cell biologists and geneticists.
How to Apply
The application process is comprised of two stages: 1) Letter of Intent, and 2)Full application.
1) Letter of Intent
In the first stage of the application process the Principal Investigator is required to submit a Letter of Intent (LOI)
The LOI must include:
- Institutional Affiliation of the Principal Investigator (academic or research position held, department, institution)
- List of co-applicants and collaborators for the proposed research
- Title of the proposal
- Title of this RFP Research Program
- Brief description (100-200 words) of the proposed research
- Amount requested from HHT Foundation International
- List of up to three suggested external referees, including contact coordinates
LOI are mandatory, and are treated with confidentiality by the HHT Foundation International and its peer-review committee. The LOI will allow the peer-review committee to relevance to the HHT Foundation’s research priorities, avoid potential conflicts of interest in the review process and select external reviewers.
The LOI should be submitted electronically to research@hht.org.
2) Full Application
Selected applicants will be invited to submit a full application by the deadline date. It is expected that the full application will generally be consistent with the LOI with respect to the outline of the research proposals and the participating investigators.
The electronic application form can be requested by emailing research@hht.org.
Letter of Intent Deadline: June 24th, 2008 by 11:59 PM Eastern Daylight Time
Application Submission Deadline: August 11th, 2008 by 11:59PM Eastern Daylight Time
